Oral leukoplakia: risk of malignant transformation and the importance of surgical excision

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Original Article

Author Details : Mariem Meddeb, Abdellatif Chokri, Faten Hammedi, Karim Masmoudi, Hajer Hentati, Jamil Selmi

Volume : 4, Issue : 3, Year : 2016

Article Page : 123-127

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Abstract

Leukoplakia is the most frequent potentially malignant lesion of the oral mucosa. Its diagnostic and therapeutic present a challenge for dentist. Two clinical cases of oral leukoplakia were reported. The first was a patient using chewed tobacco consulted for a verrucous oral lesion that was surgically completely removed. Histopathological examination of the specimen revealed verrucous carcinoma. The second was a smoker man presenting an oral leukoplakia with fungal infection. After antimycotic treatment and periodic follow up, the clinical signs of candidiasis regressed but the mucosal white patch persisted. A large part of the lesion was removed. Histopathological examination indicated a well-differentiated squamous cell carcinoma.

Keywords: Leukoplakia, Oral mucosa, Biopsy, Dysplasia, Carcinoma

How to cite : Meddeb M, Chokri A, Hammedi F, Masmoudi K, Hentati H, Selmi J, Oral leukoplakia: risk of malignant transformation and the importance of surgical excision. Int Dent J Stud Res 2016;4(3):123-127

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