Role of platelet rich plasma gel in tissue regeneration- A review

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Review Article

Author Details : Anandita Kale*, Sweta Singh

Volume : 9, Issue : 2, Year : 2021

Article Page : 73-76

https://doi.org/10.18231/j.idjsr.2021.014

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Abstract

Objectives: Platelet-rich Plasma (PRP) has been used for over a decade in operative and regenerative (medical and dental) procedures, especially oral and maxillofacial surgery and periodontics to reinforce wound healing and aid in the regeneration of lost hard and soft tissue structures.
A reasonably priced method of healing post-surgery, the plasma (which is rich in growth factors and fibrinogen) is applied in a gel-like form directly on the surgical trauma site to encourage an increased rate of wound healing and bone regeneration. Due to it being an easy extraction (autogenic or allogenic) and a rather economic approach, it has been widely accepted in various cases ranging from dental implant surgery to simple tooth extractions. This article aims to review the literature available on PRP.
Sources from which data was obtained: 1. Case evaluations and literature available in various journals; 2. correspondence with dental surgeons; 3. First-hand observation of the procedure used for extraction of PRP from venous blood for an auto-graft.
Study Selection: Plasma containing high concentrates of growth factors (which includes insulin growth factor, epidermal growth factor, platelet 4 amongst many others) used in case reports as well as literature used in bone grafts and dental implant procedures were analyzed as well as clinicians performing the technique were observed.
Conclusion: Although possessed with multiple benefits such as quicker wound healing, cellular regeneration, and anti-bacterial and anti-inflammatory properties, lack of studies show it is still in its early infancy stages of clinical application. Further studies are needed so that doctors can correctly surmise which conditions need the application of plasma gel.

Keywords: Platelet rich plasma, Growth factors, Bone regeneration, Wound healing, dental Implants

How to cite : Kale A, Singh S, Role of platelet rich plasma gel in tissue regeneration- A review. Int Dent J Stud Res 2021;9(2):73-76

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