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- DOI 10.18231/j.idjsr.2025.017
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CrossMark
- Citation
A comprehensive randomized controlled trial investigating the effectiveness of oxygene® gel in accelerating wound healing after dental extractions
- Author Details:
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Haydar Majeed Mahdey
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Anitha Krishnan Pandarathodiyil *
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Cheong Pui Jing
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Gan Lee Anne
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Chai Wei Min
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Gan Eng Sheng
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Ahmed M Daood
Background: Proper wound healing after dental extractions is crucial for minimizing complications and enhancing patient wellbeing. Oxygene® gel has been proposed as a potential adjuvant treatment aid to improve wound healing.
Objective: This study aimed to evaluate the effectiveness of Oxygene® gel in accelerating wound healing following tooth extractions through a comprehensive randomized controlled trial.
Materials and Methods: A split-mouth design was conducted on 27 patients who required dental extractions, with a total of 56 extraction sites at the Oral Surgery Clinic, Faculty of Dentistry, SEGi University. After extraction, participants applied Oxygene® gel to the socket site twice daily for two weeks, and wound healing was assessed on the 3rd and 14th days post-extraction using the Wound Healing Index. Statistical analysis was performed using the Wilcoxon Rank Test.
Results: The test group treated with Oxygene® Gel exhibited better wound healing compared to the control group. On the 3rd day, the mean wound healing score for the test group was 3.2963 (SD= 1.13730), while the control group had a mean score of 2.7037 (SD= 1.10296). After two weeks, the mean score for the test group increased to 4.0741 (SD= 0.78082), while the control group had a mean score of 3.5185 (SD= 0.97548).
Conclusion: Oxygene® gel demonstrated promising potential as an effective adjunctive therapy for accelerating wound healing following dental extractions. These findings support the integration of Oxygene® gel into routine post-extraction care protocols. Additional research is warranted to validate these results and explore further applications of Oxygene® gel in clinical dental practice.
Keywords: Oxygene®gel, Extraction socket, Wound healing, Adjunctive oral wound healing aid
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How to Cite This Article
Vancouver
Mahdey HM, Pandarathodiyil AK, Jing CP, Anne GL, Min CW, Sheng GE, Daood AM. A comprehensive randomized controlled trial investigating the effectiveness of oxygene® gel in accelerating wound healing after dental extractions [Internet]. Int Dent J Stud Res. 2025 [cited 2025 Oct 02];13(2):91-95. Available from: https://doi.org/10.18231/j.idjsr.2025.017
APA
Mahdey, H. M., Pandarathodiyil, A. K., Jing, C. P., Anne, G. L., Min, C. W., Sheng, G. E., Daood, A. M. (2025). A comprehensive randomized controlled trial investigating the effectiveness of oxygene® gel in accelerating wound healing after dental extractions. Int Dent J Stud Res, 13(2), 91-95. https://doi.org/10.18231/j.idjsr.2025.017
MLA
Mahdey, Haydar Majeed, Pandarathodiyil, Anitha Krishnan, Jing, Cheong Pui, Anne, Gan Lee, Min, Chai Wei, Sheng, Gan Eng, Daood, Ahmed M. "A comprehensive randomized controlled trial investigating the effectiveness of oxygene® gel in accelerating wound healing after dental extractions." Int Dent J Stud Res, vol. 13, no. 2, 2025, pp. 91-95. https://doi.org/10.18231/j.idjsr.2025.017
Chicago
Mahdey, H. M., Pandarathodiyil, A. K., Jing, C. P., Anne, G. L., Min, C. W., Sheng, G. E., Daood, A. M.. "A comprehensive randomized controlled trial investigating the effectiveness of oxygene® gel in accelerating wound healing after dental extractions." Int Dent J Stud Res 13, no. 2 (2025): 91-95. https://doi.org/10.18231/j.idjsr.2025.017